Glucagon Kit

What is Glucagon?

Glucagon is a medicine that’s different from insulin. It’s used to treat severe low blood sugar (severe hypoglycemia). Glucagon works by telling your body to release sugar (glucose) into the bloodstream to bring the blood sugar level back up.

Sometimes you might miss a meal, exercise too much, or not eat enough food for the amount of insulin you’ve taken. Any of these situations can lead to low blood sugar, also called hypoglycemia. If not treated quickly, mild or moderate low blood sugar can become severe. In these cases, you may be physically unable to eat or drink a rapid acting source of glucose or you may lose consciousness. You will need a Glucagon injection immediately—and a friend, family member, or coworker may need to give it to you.

Recognize the symptoms of severe low blood sugar and be ready to use Glucagon

Symptoms of severe hypoglycemia include disorientation, unconsciousness, and seizures or convulsions.

Giving a Glucagon injection can be scary, but it’s very important to recognize the symptoms of severe low blood sugar and be ready to use Glucagon. Take a moment to become familiar with your Glucagon kit—it’s small and portable and houses all the items needed to administer Glucagon in a bright red case. It’s a good idea to open the case and look at the contents. You and anyone who may need to help you with severe low blood sugar treatment should also know how to use Glucagon before an emergency arises. Be sure to read the Information for the User provided in the kit.

How to use Glucagon

Be sure to designate several people who can help in case of an emergency. In the event of severe low blood sugar (severe hypoglycemia), you will not be able to inject yourself with Glucagon. It may help you and your child feel more at ease to know that several people such as friends, the school nurse, your coach, and co-workers know where your Glucagon emergency kits are located and how to use them in case you experience severe low blood sugar. Consider asking others to download the Glucagon App and view this website.

Open Glucagon Kit

Step by step instructions on how to inject Glucagon

Step 1

Step 1

Flip off the seal from the vial of Glucagon powder.

Step 2

Step 2

Remove the needle cover from the syringe. DO NOT REMOVE THE PLASTIC CLIP FROM THE SYRINGE, as this may allow the push rod to come out of the syringe.

Step 3

Step 3

Insert the needle into the rubber stopper on the vial, then inject the entire contents of the syringe into the vial of Glucagon powder.

Step 4

Step 4

Remove the syringe from the vial, then gently swirl the vial until the liquid becomes clear. Glucagon should not be used unless the solution is clear and of a water-like consistency.

Step 5

Step 5

Insert the same syringe into the vial and slowly withdraw all the liquid. To use on children weighing less than 44 pounds, withdraw half of the liquid (0.5 mark on the syringe).

Step 6

Step 6

Cleanse site on buttock, arm, or thigh and inject Glucagon immediately after mixing, and then withdraw the needle. Apply light pressure against the injection site.

Step 7

Step 7

Turn the person on his/her side. When an unconscious person awakens, he/she may vomit.

Call 911 immediately after administering Glucagon. If the person does not awaken within 15 minutes, give another dose of Glucagon and inform a doctor or emergency services immediately.

Step 7 continued

Step 7 continued

As soon as the person is awake and able to swallow, give him/her a fast-acting source of sugar (such as fruit juice), followed by a snack or meal containing both protein and carbohydrates (such as cheese and crackers, or a peanut butter sandwich).

Step 8

Step 8

Discard any unused reconstituted Glucagon.

Remember to notify your healthcare provider that an episode of severe hypoglycemia has occurred.

These are not the complete instructions. Go to Information for the User for complete instructions on how to administer Glucagon.

Tips for hypoglycemic emergencies for children and adults

Be prepared with multiple kits

Make sure you always have a Glucagon emergency kit with your other diabetes supplies when you’re away from home. It’s important to have more than one kit and consider keeping one at school, at work, with close relatives, and in places where you or your child spend a lot of time. Close friends, co-workers, family members, school nurses, and coaches should know where your kits are and how to use them.

Multiple Glucagon Kits
Father and Child

Places to keep Glucagon kits

For children
  • in the school nurse’s office
  • at daycare or with the sitter
  • with the coach
  • at homes of relatives
For adults
  • at the workplace
  • with you when traveling
  • at the homes of close friends
  • in your college dorm room

Ask your doctor about prescribing more than one Glucagon kit. Your insurance plan may allow you to receive more than one kit with only one co-pay.

Check your Glucagon emergency kit’s expiration date

Severe low blood sugar can happen anytime, which makes it important to plan ahead. Look at your kit’s expiration date each time you get a new prescription. The expiration date can be found on the outside label under “Exp. Date/Control No.” on the outer red case, and also on the bottle.* The date will be written as mm yyyy to reflect the month and year of expiration. An expired Glucagon kit should never be used.

  • Check your kit’s expiration date
  • Add your kit’s expiration date to your calendar one month before it expires
  • Ask your doctor for a new prescription

You can also set reminders with the Manage My Kits feature within the FREE Glucagon App.

*Although the expiration date on the outside of the kit may be different than the expiration date on the syringe or bottle, it is the outer date (on the back of the red box) you should always refer to. The kit (as a whole) expires when the earliest expiration date of any of the items contained in the kit occurs.

The expiration date can be found on the back of your Glucagon kit.

Back of a Glucagon Kit
Indication and Important Safety Information

Glucagon is a treatment for very low blood sugar (severe hypoglycemia) which may occur in patients with diabetes. Symptoms include disorientation, unconsciousness, and seizures or convulsions.


What is the most important information I should know about Glucagon?

  • You should NOT use Glucagon if you have a pheochromocytoma or if you are allergic to Glucagon. (A pheochromocytoma is a tumor, typically of the adrenal gland, that may lead to increased heart rate, blood pressure, sweating, and anxiety.)
  • Make sure you tell your healthcare provider if you have been diagnosed with or have been suspected of having an insulinoma, as Glucagon should be used cautiously in this situation. (An insulinoma is a pancreatic tumor that secretes insulin.)
  • You and anyone who may need to help you if your blood sugar becomes very low (severely hypoglycemic), should become familiar with how to use Glucagon before an emergency arises. Read the Information for the User provided in the kit.
  • Make sure that your relatives or close friends know that if you become unconscious, medical assistance must always be sought. If you are unconscious, Glucagon can be given while awaiting medical assistance.
  • Do not use the kit after the date stamped on the vial of Glucagon.
  • If you have questions concerning the use of this product, consult a doctor, nurse, or pharmacist.


What are the possible side effects of Glucagon?
  • Side effects may include nausea and vomiting, a temporary increase in heart rate, and allergic reactions to Glucagon or to one of the inactive ingredients in Glucagon.

You are encouraged to report negative side effects of Prescription drugs to the Food and Drug Administration (FDA). Visit or call 1-800-FDA-1088.

How should I take Glucagon?
  • Act quickly. Prolonged unconsciousness may be harmful.
  • Make sure your family and friends know to turn you on your side to prevent choking if you are unconscious.
  • The contents of the syringe are inactive and must be mixed with the Glucagon in the accompanying vial immediately before giving the injection. Do not prepare Glucagon for Injection until you are ready to use it.
  • Glucagon should not be used unless the solution is clear and of a water-like consistency.
  • The usual adult dose is 1 mg. For children weighing less than 44 lbs (20 kg), give ½ adult dose (0.5 mg). For children, withdraw ½ of the solution from the vial (0.5 mg mark on syringe). Discard unused portion.
  • You should eat as soon as you awaken and are able to swallow. Inform a doctor or emergency services immediately.
How should I store Glucagon?
  • Store the kit at controlled room temperature between 20° to 25°C (68° to 77°F) before mixing Glucagon with the diluent.
  • Glucagon that has been mixed with diluent should be used immediately. Discard any unused portion. Glucagon should be clear and of a water-like consistency at time of use.
Glucagon is available by prescription only

For more safety information, please see Information for the User and Information for the Physician.